- Scope:This Standard Operating Procedure is applicable to the formulation plant of Pharmaceutical Company(Make-Neela Metal ,Capacity -2.5m3/hr) .
- Objective:To lay down an Operating Procedure for Purified Water Generation System.
- Volts: Voltage
- Amps : Amperes
- PH : Proportionate Hydrogen
- Kg/cm2 :Kilogram per Centimeter Square
- m3/hr :Meter Cube per Hour
- µS/Cm: Micro Siemens per Centimeter
- UF: Ultra Filtrations
- EDI :Electro Deionization
- MCF: Micron Cartridge Filter
- NMT: Not More Than
- NLT: Not Less Than
- HPP: High Pressure Pump
- RO: Reverse Osmosis
- Abbreviations and Definitions:
- Accountability:Head-Engineering and QA shall be accountable for the compliance of the procedure as per this SOP.
- Responsibility
- The Concerned Technician shall follow the Operating Procedure as per this SOP.
- The Officer/Executive-Engineering shall be responsible for implementation of the procedure as per this SOP.
- Procedure
- Switch “ON” the main switch of RO- panel.
- Open the soft water supply pump suction valve and discharge valve
- Start the soft water pump.
- Start the dosing of anti-scalent and PH- correction.
- Check the free chlorine and pH on ORP meter and PH check point.
- Remove the air from MCF through vent valve.
- Start the HPP and flush the RO-1 membranes for 5 to 10 minutes.
- Adjust Valve to desired pressure and flow.
- Membrane inlet water pressure – NMT 6.8 kg/ cm2.
- Permeate water flow -NLT 3.66 m3/hr.
- Reject water pressure between 4 to 5 Kg/cm2.
- Reject water recirculation -NLT 2.5 m3/ hr.
- Start the HPP and flush the RO -2 for 5 to 10 minutes.
- Adjust the V to design pressure and flow. (RO-]2)
- Membrane inlet water pressure between 6 to 7 kg / cm2
- Permeate water flow – NLT 3 m3 / hr.
- Reject water pressure between 3 to 4 kg / cm2.
- Reject water recirculation flow 1.5 to 2 m3/ hr.
- Start EDI feed pumps.
- When water comes out from EDI start the rectifier..
- Ensure the valve is completely open.
- EDI inlet water pressure – NMT 3.0 Kg/cm2.
- Permeate water flow – 2.6 m3/ hr.
- Start the rectifier and adjust the current (6Amps-10Amps) and voltage (200Volts-300Volts) for required quality of water.
- Adjust the Valve for the desired water flow from UF.
- Permeate water flow – 2.5 m3/ hr.
- Reject water pressure between 0.2 to 0.4 Kg / cm2.
- Record all the observation of Purified Water System in the Log Sheet. As per Operation.
- Parameter Conductivity should be less than 60 µS /Cm for RO-1, less than 40 µS /Cm for RO-2 and less than 1.3 µS /Cm for after EDI and UF outlet.
- Forms and Annexure
- Logbook of Purified Water System : Annexure-I
- Distribution:
- Master Copy: Documentation Cell
- Controlled Copies: Engineering, Production, Quality Assurance,Warehouse, Quality Control, Administration and House Keeping
- History:
| Date | Revision Number |
Reason for Revision |
| – | 00 | New SOP |
