Hot Water Sanitization Procedure of Purified Water Distribution Loop

• Hot Water Sanitization Procedure of Purified Water Distribution Loop

• Objective : To ensure that the Purified Water Distribution Loop along with the tank is sanitized at 85 degree Centigrade to reduce the microbial count.
• Scope :
• Procedure :
• Fill the Purified Water Storage Tank till the Half Level.
• Ensure Suction & Discharge valve of pump are open and all user points & sampling valves are closed.
• Sanitization is required during the Start up of the system, once it is chemically cleaned.
• Open Steam Valve and Start elevating the temperature.
• When the temperature in the return line reaches 85 degree Centigrade, close the Steam Valve.
• Recirculate the Hot Water for 60 minutes.
• If the temperature decreases to 80 degree Centigrade, Open the Steam Valve.
• Drain the Hot Water from all equipments, user points & sampling points.
• Take fresh RO Water and start the system and keep it under recirculation at 85 degree Centigrade.
• Handover the System to Validation department for taking samples.
• Observation should be filled in Sanitization Record Sheet.

Pharma More Jobs and post Please click here